Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105689 | 0.71 | F2 (0.39) | — | |
| SCHEMBL7436462 | 0.70 | NPC1 (0.36) | — | |
| SCHEMBL28766776 | 0.69 | — | — | |
| SCHEMBL28871 | 0.68 | HDAC8 (0.59) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL27563745 | 0.65 | MAPT (0.44) | — | |
| SCHEMBL28704374 | 0.65 | AKR1C3 (0.53) | AKR1C3 | |
| SCHEMBL578312 | 0.65 | AKR1C3 (0.53) | AKR1C3 | |
| SCHEMBL10481152 | 0.65 | HDAC8 (0.56) | AKR1C3HDAC8CA12CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL22721248 | 0.65 | HDAC8 (0.56) | AKR1C3HDAC8CA12CA1CA2 | |
| SCHEMBL10929982 | 0.64 | MAPT (0.50) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158963-A | Cognition activators; improve brain function | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0411549-A1 | 1,4-dihydropyridine derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1991-02-06 | — | — | EP | disclosed |