SCHEMBL1105689

SCHEMBL1105689

Cc1ccc(N2C=CCC=C2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.39
ELANE P08246 1/20 0.39
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39
CTRC Q99895 1/20 0.39
ADRB1 P08588 1/20 0.39
TDP1 Q9NUW8 3/20 0.38
ACHE P22303 1/20 0.38
MGLL Q99685 1/20 0.37
MAPT P10636 5/20 0.36
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
ALDH1A1 P00352 2/20 0.35
GAA P10253 2/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALOX5 P09917 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12230241 0.82 ACHE (0.50) F2ELANECTSGCMA1CTRC
SCHEMBL22430825 0.75 ELANE (0.42) F2ELANECTSGCMA1CTRC
SCHEMBL7436462 0.75 NPC1 (0.36) ADRB1TDP1MGLLMAPTLMNA
SCHEMBL28766776 0.73
P-Xylene SCHEMBL1376667 0.73 ACHE (0.61) TDP1ACHELMNAALDH1A1GAA
SCHEMBL28357023 0.71 F2 (0.39) F2ELANECTSGCMA1CTRC
SCHEMBL9733019 0.71 AKR1C3 (0.36)
SCHEMBL18025876 0.70 CACNA1B (0.39) F2ELANECTSGCMA1CTRC
SCHEMBL10929982 0.69 MAPT (0.50) ADRB1ACHEMAPTLMNAALDH1A1
SCHEMBL5854414 0.67 ADRB1 (0.54) F2ELANECTSGCMA1CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4008790-B1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS ENZO BIOCHEM INC (US) 2024-07-17 EP disclosed
EP-4008790-A1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS Enzo Biochem, Inc. (US) 2022-06-08 EP disclosed
EP-3277832-B1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS ENZO BIOCHEM INC (US) 2021-10-06 EP disclosed
US-20210079225-A1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS ENZO BIOCHEM, INC. (US) 2021-03-18 US disclosed
EP-2982245-B1 CYANINE DYES FOR LABELING OF TARGET MOLECULES, IDENTIFICATION OF ORGANELLES AND OTHER APPLICATIONS ENZO LIFE SCIENCES INC (US) 2018-08-08 EP disclosed
US-20180215920-A1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCERS ENZO BIOCHEM, INC. (US) 2018-08-02 US disclosed
US-20180215920-A1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCERS ENZO BIOCHEM, INC. (US) 2018-08-02 US disclosed
US-9957393-B2 Monoazo dyes with cyclic amine as fluorescence quenchers ENZO BIOCHEM, INC. (US) 2018-05-01 US disclosed
US-9957393-B2 Monoazo dyes with cyclic amine as fluorescence quenchers ENZO BIOCHEM, INC. (US) 2018-05-01 US disclosed
US-9951227-B2 Monoazo dyes with cyclic amine as fluorescence quenchers ENZO BIOCHEM, INC. (US) 2018-04-24 US disclosed
WO-2010065918-A1 LABELING OF TARGET MOLECULES, IDENTIFICATION OF ORGANELLES AND OTHER APPLICATIONS, NOVEL COMPOSITIONS, METHODS AND KITS ENZO LIFE SCIENCES, INC. (US) 2010-06-10 WO disclosed
US-20100093004-A1 Autophagy and phospholipidosis pathway assays ENZO LIFE SCIENCES, INC. 2010-04-15 US disclosed
US-20100093004-A1 Autophagy and phospholipidosis pathway assays ENZO LIFE SCIENCES, INC. 2010-04-15 US disclosed
US-20100068752-A1 Novel fluorescent dyes and compounds, methods and kits useful for identifying specific organelles and regions in cells of interest ENZO LIFE SCIENCES, INC. 2010-03-18 US disclosed
US-20100041020-A1 Methods for detecting the presence, location or quantity of targets using novel dyes ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2010-02-18 US disclosed
US-20100041020-A1 Methods for detecting the presence, location or quantity of targets using novel dyes ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2010-02-18 US disclosed
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits ENZO LIFE SCIENCES, INC. 2009-09-10 US disclosed
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits ENZO LIFE SCIENCES, INC. 2009-09-10 US disclosed
US-7569695-B2 Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization ENZO LIFE SCIENCES, INC. (US) 2009-08-04 US disclosed
US-7569695-B2 Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization ENZO LIFE SCIENCES, INC. (US) 2009-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits SSBP1, IMMT, DNAJA3 F2 4869/4885ELANE 3524/4885CTSG 1903/4885
US-20100068752-A1 Novel fluorescent dyes and compounds, methods and kits useful for identifying specific organelles and regions in cells of interest SSBP1, YARS1, ANXA5 F2 4866/4885ELANE 3029/4885CTSG 2106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.