SCHEMBL9733160

SCHEMBL9733160

CC(=O)NNS(=O)(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 1/20 1.00
GAA P10253 4/20 0.66
KAT6A Q92794 5/20 0.65
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
HTT P42858 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
IDO1 P14902 1/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPT P10636 1/20 0.54
THRB P10828 1/20 0.53
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
MMP13 P45452 1/20 0.52
LMNA P02545 1/20 0.52
POLB P06746 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11532705 0.83 BCAT1 (0.71) BCAT1GAAKAT6AMEN1KMT2A
SCHEMBL11513730 0.81 MEN1 (0.72) BCAT1GAAKAT6AMEN1KMT2A
SCHEMBL7633153 0.81 BCAT1 (0.68) BCAT1GAAKAT6AMEN1KMT2A
SCHEMBL11358251 0.81 TDP1 (0.68) BCAT1GAAMEN1KMT2ASMN1; SMN2
SCHEMBL7644248 0.80 BCAT1 (0.67) BCAT1GAAKAT6AMEN1KMT2A
SCHEMBL2361900 0.80 BCAT1 (0.67) BCAT1GAAKAT6AMEN1KMT2A
SCHEMBL14679321 0.79 HTT (0.66) BCAT1GAAKAT6AMEN1KMT2A
SCHEMBL209632 0.79 DHFR (0.66) BCAT1KMT2AHTTSMN1; SMN2CA1
SCHEMBL2746048 0.79 BCAT1 (0.65) BCAT1GAAKAT6AMEN1KMT2A
SCHEMBL4765513 0.78 KAT6A (1.00) BCAT1GAAKAT6AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3966651-A Process for the production of fine-cell polyolefin foams BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed
CN-113563562-B Disc-type self-repairing safety tire rubber material and preparation method thereof 无锡安睿驰科技有限公司 2022-05-13 CN disclosed
CN-113563562-A Disc-type self-repairing safety tire rubber material and preparation method thereof 无锡安睿驰科技有限公司 2021-10-29 CN disclosed
WO-2014152013-A1 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2014-09-25 WO disclosed
CN-1355807-A Thiazoloindolinone compounds GLAXO GROUP LTD (GB) 2002-06-26 CN disclosed
WO-1992007836-A1 NOVEL SULFAMIDE DERIVATIVES, A METHOD FOR OBTAINING THEM AND THEIR USE AS A DRUG SHIMI IBRAHIM RAOUF (FR) 1992-05-14 WO disclosed
US-3966651-A Process for the production of fine-cell polyolefin foams BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed