Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TOP2A | P11388 | 6/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732019 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL9442767 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| Hydrochloric Acid SCHEMBL28456435 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10368718 | 0.85 | ALDH1A1 (0.55) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| Hydrochloric Acid SCHEMBL9731762 | 0.84 | ALDH1A1 (0.54) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL9731919 | 0.83 | LMNA (0.55) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9732036 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10572627 | 0.82 | ALDH1A1 (0.57) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL9732051 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL9731681 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1TOP2ATOP2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081254-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4929613-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0306764-A2 | 4-Quinolone-3-carboxylic-acid derivatives and their use as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |