Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733401 | 1.00 | MYC (0.39) | MYCHTR6ELANEKMT2ATTR | |
| SCHEMBL9733094 | 0.82 | CA2 (0.42) | HTR6CA1CA2CA5ACA9 | |
| SCHEMBL9733101 | 0.82 | CA2 (0.42) | HTR6CA1CA2CA5ACA9 | |
| SCHEMBL28686688 | 0.80 | HTR6 (0.53) | HTR6KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL27824775 | 0.79 | MYC (0.38) | MYCHTR6ELANEKMT2ATTR | |
| SCHEMBL27957388 | 0.78 | MYC (0.37) | MYCHTR6ELANEKMT2ATTR | |
| SCHEMBL2723950 | 0.78 | MYC (0.37) | MYCHTR6ELANEKMT2ATTR | |
| SCHEMBL8356271 | 0.77 | HSD17B10 (0.38) | MYCHTR6ELANEKMT2ATTR | |
| SCHEMBL28440193 | 0.76 | MYC (0.36) | MYCHTR6ELANEKMT2ATTR | |
| Bromide SCHEMBL11100956 | 0.76 | MYC (0.36) | MYCHTR6ELANEKMT2ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096917-A | Antiallergens; treatment of asthma, hay fever, genetic disorders | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |