Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460483 | 1.00 | ACE (0.40) | ACELMNAMEN1KMT2AUSP2 | |
| Hydrochloric Acid SCHEMBL9732651 | 0.99 | ACE (0.40) | ACELMNAMEN1KMT2AUSP2 | |
| Hydrochloric Acid SCHEMBL10741835 | 0.99 | ACE (0.40) | ACELMNAMEN1KMT2AUSP2 | |
| Trifluoroacetic Acid SCHEMBL10742756 | 0.95 | ACE (0.37) | ACELMNAMEN1KMT2AUSP2 | |
| SCHEMBL10735598 | 0.91 | ACE (0.35) | ACELMNAMEN1KMT2AUSP2 | |
| SCHEMBL10742800 | 0.91 | ACE (0.35) | ACELMNAMEN1KMT2AUSP2 | |
| Hydrochloric Acid SCHEMBL10742610 | 0.85 | KMT2A (0.38) | ACEMEN1KMT2A | |
| SCHEMBL10742946 | 0.85 | ALDH1A1 (0.33) | SMN1; SMN2 | |
| SCHEMBL5794084 | 0.84 | ACE (0.48) | ACELMNAMEN1KMT2AUSP2 | |
| SCHEMBL9520888 | 0.84 | ACE (0.48) | ACELMNAMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175306-A | Intermediates for hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-29 | — | — | US | disclosed |
| US-4822894-A | PURE CIS ENANTIOMERS OF FUSED PYRROLE RING CARBOXYLATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-18 | — | — | US | disclosed |
| US-4668797-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-26 | — | — | US | disclosed |
| US-4668796-A | Racemates of optically active bicyclic imino-alpha-carboxylic esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-26 | — | — | US | disclosed |
| US-4562202-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | disclosed |