Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.64 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578274 | 0.81 | CYP3A4 (0.58) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL2502464 | 0.81 | TSHR (0.56) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL2495842 | 0.81 | AHR (0.52) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL29962162 | 0.78 | AHR (0.54) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL331060 | 0.78 | AHR (0.54) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL29366153 | 0.78 | AHR (1.00) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL2279480 | 0.78 | AHR (1.00) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL597055 | 0.78 | AHR (0.48) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL2493219 | 0.78 | AHR (0.50) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL29962749 | 0.78 | AHR (0.48) | AHRDHFRNPC1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145790-A | Immunoassay, fluorescein derivative | ABBOTT LABORATORIES (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0455058-A2 | Reagents and method for detecting polychlorinated biphenyls | ABBOTT LABORATORIES (US) | 1991-11-06 | — | — | EP | disclosed |