Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | DHFR | P00374 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962162 | 1.00 | AHR (0.54) | AHRALDH1A1HSD17B10PTGER1PTGER3 | |
| SCHEMBL1300021 | 0.88 | ALDH1A1 (0.61) | AHRALDH1A1HSD17B10PTGER1PTGER3 | |
| SCHEMBL23502859 | 0.86 | ALDH1A1 (0.52) | AHRALDH1A1HSD17B10PTGER1PTGER3 | |
| SCHEMBL15364609 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HSD17B10PTGER1PTGER3PTGER2 | |
| SCHEMBL31161110 | 0.82 | PTGS2 (0.58) | ALDH1A1HSD17B10ADORA1L3MBTL1DHFR | |
| SCHEMBL18238557 | 0.82 | ESR2 (0.58) | ALDH1A1HSD17B10ADORA1L3MBTL1DHFR | |
| SCHEMBL3904951 | 0.82 | FEN1 (0.51) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL8098489 | 0.82 | CYP3A4 (0.48) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL397260 | 0.82 | PTGS2 (0.58) | ALDH1A1HSD17B10ADORA1L3MBTL1DHFR | |
| SCHEMBL1558220 | 0.81 | ALDH1A1 (0.54) | AHRALDH1A1HSD17B10L3MBTL1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500551-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2021-11-10 | — | — | EP | claimed |
| US-10683256-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2020-06-16 | — | — | US | claimed |
| CN-111056950-A | Method for preparing 3', 4' -dichloro-2-aminobiphenyl | 广东石油化工学院 | 2020-04-24 | — | — | CN | claimed |
| US-20190210954-A1 | Process for Preparing Substituted Biphenyls | LIANHE CHEMICAL TECHNOLOGY CO., LTD (CN) | 2019-07-11 | — | — | US | claimed |
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | claimed |
| EP-3500551-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2021-11-10 | — | — | EP | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10683256-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2020-06-16 | — | — | US | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| CN-111056950-A | Method for preparing 3', 4' -dichloro-2-aminobiphenyl | 广东石油化工学院 | 2020-04-24 | — | — | CN | disclosed |
| CN-111056950-A | Method for preparing 3', 4' -dichloro-2-aminobiphenyl | 广东石油化工学院 | 2020-04-24 | — | — | CN | disclosed |
| CN-111056950-A | Method for preparing 3', 4' -dichloro-2-aminobiphenyl | 广东石油化工学院 | 2020-04-24 | — | — | CN | disclosed |
| WO-2006121218-A1 | N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-11-16 | — | — | WO | disclosed |
| EP-1713789-A1 | 2-HALOFURYL/THIENYL-3-CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2006097490-A1 | NICOTINANILIDES METHOD FOR PRODUCTION THEREOF AND AGENTS COMPRISING THE SAME FOR PREVENTION OF FUNGAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-21 | — | — | WO | disclosed |
| WO-2006087343-A1 | PYRAZOLE CARBOXYLIC ACID ANILIDES, METHOD FOR THE PRODUCTION THEREOF AND AGENTS CONTAINING THEM FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-24 | — | — | WO | disclosed |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | VERTEX PHARMACEUTICALS INCORPORATED | 2006-04-06 | — | — | US | disclosed |
| WO-2005123689-A1 | 1-METHYL-3-TRIFLUOROMETHYL-PYRAZOLE-4-CARBOXYLIC ACID (ORTHO-PHENYL)-ANILIDES AND TO USE THEREOF AS FUNGICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-29 | — | — | WO | disclosed |
| WO-2005075452-A1 | 2-HALOFURYL/THIENYL-3-CARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |
| US-5455252-A | Antiinflammatory agent, immunosuppressant, antiallergen, skin disorders, bronchodilator, analgesic | SYNTEX (U.S.A.) INC. (US) | 1995-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683256-B2 | Process for preparing substituted biphenyls | PIK3CA, PIK3CB, PIK3CG | AHR 122/4885ALDH1A1 3096/4885HSD17B10 3163/4885 |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | AHR 954/4885ALDH1A1 2165/4885HSD17B10 1468/4885 |
| US-20190210954-A1 | Process for Preparing Substituted Biphenyls | PIK3CA, PIK3CB, PIK3CG | AHR 122/4885ALDH1A1 3096/4885HSD17B10 3163/4885 |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | CFTR, ABCC4, ABCC2 | AHR 1841/4885ALDH1A1 2221/4885HSD17B10 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.