Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962749 | 0.85 | AHR (0.48) | AHRDHFRNPC1RAB9APSEN1 | |
| SCHEMBL597055 | 0.85 | AHR (0.48) | AHRDHFRNPC1RAB9APSEN1 | |
| Hydrochloric Acid SCHEMBL31475440 | 0.84 | ALDH1A1 (0.48) | AHRDHFRNPC1RAB9APSEN1 | |
| Hydrochloric Acid SCHEMBL31475434 | 0.84 | ALDH1A1 (0.48) | AHRDHFRNPC1RAB9APSEN1 | |
| Hydrochloric Acid SCHEMBL31475438 | 0.84 | ALDH1A1 (0.48) | AHRDHFRNPC1RAB9APSEN1 | |
| SCHEMBL2502464 | 0.81 | TSHR (0.56) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL3793523 | 0.78 | TAAR1 (0.52) | APPCYP3A4ALDH1A1MAPK1MAPT | |
| SCHEMBL9733580 | 0.78 | AHR (0.64) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL27412108 | 0.78 | AHR (0.50) | AHRDHFRNPC1RAB9ACYP3A4 | |
| SCHEMBL2501033 | 0.77 | ALDH1A1 (0.45) | DHFRALDH1A1AKR1C3AKR1C2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819223-B1 | USE OF MENADIONE FOR BOOSTING THE EFFECTIVENESS OF AGROCHEMICALS | BASF SE (DE) | 2008-03-12 | — | — | EP | claimed |
| US-8030527-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2011-10-04 | — | — | US | disclosed |
| US-20100256418-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | SMIDT SEBASTIAN PEER | 2010-10-07 | — | — | US | disclosed |
| US-7709684-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2010-05-04 | — | — | US | disclosed |
| EP-2029519-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2009-03-04 | — | — | EP | disclosed |
| US-20090005597-A1 | Process for Preparing Substituted Biphenyls | BASF SE (DE) | 2009-01-01 | — | — | US | disclosed |
| WO-2007138089-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2007-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256418-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | CBR3, HRH3, CBR1 | AHR 12/4885DHFR 1773/4885NPC1 2519/4885 |
| US-20090005597-A1 | Process for Preparing Substituted Biphenyls | CBR3, HRH3, CBR1 | AHR 24/4885DHFR 1279/4885NPC1 1656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.