Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854415 | 0.85 | HSD17B10 (0.48) | CA9HSD17B10CASP1CASP7MAOB | |
| SCHEMBL18982690 | 0.78 | MAOB (0.44) | HSD17B10MAOBALDH2ALDH3A1TSHR | |
| SCHEMBL5799941 | 0.77 | ALDH2 (0.47) | CA9MAOBALDH2ALDH3A1TSHR | |
| SCHEMBL8759192 | 0.77 | MAOB (0.43) | MAOBALDH2ALDH3A1MAPTLMNA | |
| SCHEMBL1013856 | 0.77 | CA2 (0.50) | CA9HSD17B10MAOBALDH2ALDH3A1 | |
| SCHEMBL13950589 | 0.77 | MAOB (0.50) | HSD17B10MAOBALDH2ALDH3A1TSHR | |
| SCHEMBL29448284 | 0.77 | CA2 (0.50) | CA9HSD17B10MAOBALDH2ALDH3A1 | |
| SCHEMBL14192627 | 0.74 | ALDH2 (0.51) | HSD17B10MAOBALDH2ALDH3A1TSHR | |
| SCHEMBL26314663 | 0.74 | ALDH1A1 (0.43) | CA9MAOBALDH2ALDH3A1MAPT | |
| SCHEMBL27762668 | 0.74 | PARP1 (0.45) | HSD17B10MAOBALDH2ALDH3A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215848-B | Protein kinase inhibitor and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-110467620-A | Novel S type or R type tetrahydronaphthalene amides compound and its pharmaceutically acceptable salt and preparation method and application | UNIV LIAONING | 2019-11-19 | — | — | CN | disclosed |
| WO-2016187667-A1 | FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS | NOVOGEN LIMITED (AU) | 2016-12-01 | — | — | WO | disclosed |
| US-5081044-A | Detection of hydrogen peroxide with optical indicator chalcogen compounds | MILES INC. (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0156261-B1 | FLUOROGENIC DIHYDROQUINOLONE AND DIHYDROCOUMARIN INDICATORS FOR HYDROGEN PEROXIDE | MILES INC. (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4996332-A | On oxidation produce fluorescent signals in analytical systems | MILES INC. (US) | 1991-02-26 | — | — | US | disclosed |
| US-4794079-A | PEROXIDASE | MILES INC. (US) | 1988-12-27 | — | — | US | disclosed |
| US-4778893-A | FLUORESCENT; OXIDATION OF CHALCOGENS WITH HYDROGEN PEROXIDE | MILES INC. (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0121743-B1 | OPTICAL INDICATOR CHALCOGEN COMPOUNDS AND USE | MILES LABORATORIES, INC. (US) | 1987-09-09 | — | — | EP | disclosed |
| US-4558130-A | FLUORESCENCE ON OXIDATION BY HYDROGEN PEROXIDE; PEROXIDASE DETERMINATION | MILES LABORATORIES, INC. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0156261-A2 | Fluorogenic dihydroquinolone and dihydrocoumarin indicators for hydrogen peroxide | MILES INC. (US) | 1985-10-02 | — | — | EP | disclosed |
| EP-0121743-A2 | Optical indicator chalcogen compounds and use | MILES LABORATORIES, INC. (US) | 1984-10-17 | — | — | EP | disclosed |