Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938753 | 0.98 | HTT (0.60) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL10413156 | 0.98 | HTT (0.60) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL19014762 | 0.93 | CA12 (0.58) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| Iodide SCHEMBL22068772 | 0.92 | CA2 (0.59) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL8818892 | 0.90 | TDP1 (0.68) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL4126086 | 0.90 | MEN1 (0.60) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL18179825 | 0.90 | MEN1 (0.60) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL9852204 | 0.90 | MEN1 (0.60) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL28853028 | 0.89 | ACHE (0.56) | HTTLMNASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL19014763 | 0.87 | HTT (0.50) | HTTLMNASMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086192-A | Photopolymerizable compositions and photoinitiators therefor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-02-04 | — | — | US | disclosed |