Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | BACE1 | P56817 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7882404 | 0.89 | PTGS2 (0.55) | PTGS2BACE1MAPTGLO1ACHE | |
| SCHEMBL18371948 | 0.85 | MAPT (0.60) | MAPTGLO1NPSR1KDM4EALDH1A1 | |
| SCHEMBL7818630 | 0.84 | GLO1 (0.59) | MAPTGLO1NPSR1KDM4EALDH1A1 | |
| SCHEMBL7828149 | 0.82 | MAPT (0.49) | MAPTGLO1NPSR1KDM4EALDH1A1 | |
| SCHEMBL14492424 | 0.82 | MAPT (0.55) | MAPTGLO1NPSR1KDM4EALDH1A1 | |
| SCHEMBL7817919 | 0.81 | MAPT (0.48) | MAPTGLO1NPSR1KDM4EALDH1A1 | |
| SCHEMBL17049220 | 0.81 | MAPT (0.66) | BACE1MAPTGLO1NPSR1KDM4E | |
| Potassium Ion SCHEMBL7817917 | 0.81 | MAPT (0.48) | MAPTGLO1NPSR1KDM4EALDH1A1 | |
| SCHEMBL9835313 | 0.81 | MAPT (0.50) | MAPTGLO1NPSR1KDM4EALDH1A1 | |
| SCHEMBL1373654 | 0.80 | MAPT (0.71) | MAPTGLO1ACHENPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081044-A | Detection of hydrogen peroxide with optical indicator chalcogen compounds | MILES INC. (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0156261-B1 | FLUOROGENIC DIHYDROQUINOLONE AND DIHYDROCOUMARIN INDICATORS FOR HYDROGEN PEROXIDE | MILES INC. (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4996332-A | On oxidation produce fluorescent signals in analytical systems | MILES INC. (US) | 1991-02-26 | — | — | US | disclosed |
| US-4794079-A | PEROXIDASE | MILES INC. (US) | 1988-12-27 | — | — | US | disclosed |
| US-4778893-A | FLUORESCENT; OXIDATION OF CHALCOGENS WITH HYDROGEN PEROXIDE | MILES INC. (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0121743-B1 | OPTICAL INDICATOR CHALCOGEN COMPOUNDS AND USE | MILES LABORATORIES, INC. (US) | 1987-09-09 | — | — | EP | disclosed |
| US-4558130-A | FLUORESCENCE ON OXIDATION BY HYDROGEN PEROXIDE; PEROXIDASE DETERMINATION | MILES LABORATORIES, INC. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0156261-A2 | Fluorogenic dihydroquinolone and dihydrocoumarin indicators for hydrogen peroxide | MILES INC. (US) | 1985-10-02 | — | — | EP | disclosed |
| EP-0121743-A2 | Optical indicator chalcogen compounds and use | MILES LABORATORIES, INC. (US) | 1984-10-17 | — | — | EP | disclosed |