Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734442 | 0.91 | MAPT (0.55) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL5573539 | 0.90 | MAPT (0.73) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL5573492 | 0.88 | MAPT (0.71) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL9733841 | 0.88 | MAPT (0.52) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL9416948 | 0.86 | MAPT (0.78) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL9416988 | 0.80 | MAPT (0.69) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL9736352 | 0.79 | MAPK1 (0.44) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL7307532 | 0.79 | MAPT (0.68) | MAPTMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL9416936 | 0.79 | MAPT (1.00) | MAPTMAPK1MEN1KMT2AGSR | |
| SCHEMBL9734778 | 0.78 | MAPK1 (0.49) | MAPTMAPK1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0434185-A2 | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-26 | — | — | EP | disclosed |