Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733841 | 0.91 | MAPT (0.52) | MAPK1CYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL9733979 | 0.90 | MAPK1 (0.46) | MAPK1CYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL9734442 | 0.85 | MAPT (0.55) | MAPK1CYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL9734929 | 0.80 | KDM4E (0.51) | MAPK1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9734778 | 0.79 | MAPK1 (0.49) | MAPK1CYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL9733983 | 0.79 | MAPT (0.65) | MAPK1CYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL9734904 | 0.78 | MAPK1 (0.43) | MAPK1CYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL9734058 | 0.74 | ALDH1A1 (0.56) | MAPK1CYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL3380016 | 0.71 | KDM4E (0.59) | MAPK1CYP1A2CYP2D6MAPTKDM4E | |
| SCHEMBL9734834 | 0.70 | MAPT (0.48) | MAPK1CYP1A2CYP2D6MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0434185-A2 | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-26 | — | — | EP | disclosed |