Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416948 | 0.88 | MAPT (0.78) | MAPTMAPK1MEN1KMT2AGSR | |
| SCHEMBL5573539 | 0.85 | MAPT (0.73) | MAPTMAPK1MEN1KMT2AGSR | |
| SCHEMBL5573492 | 0.83 | MAPT (0.71) | MAPTMAPK1MEN1KMT2AGSR | |
| SCHEMBL9416988 | 0.82 | MAPT (0.69) | MAPTMAPK1MEN1KMT2AGSR | |
| SCHEMBL9416936 | 0.81 | MAPT (1.00) | MAPTMAPK1MEN1KMT2AGSR | |
| SCHEMBL9733983 | 0.79 | MAPT (0.65) | MAPTMAPK1MEN1KMT2AGSR | |
| SCHEMBL7098425 | 0.78 | SIGMAR1 (0.50) | MAPTMEN1KMT2ASIGMAR1CXCR4 | |
| SCHEMBL8293827 | 0.75 | SIGMAR1 (0.55) | MEN1KMT2ASIGMAR1CXCR4TDP1 | |
| SCHEMBL20865904 | 0.75 | SIGMAR1 (0.44) | MAPTMEN1KMT2ASIGMAR1CXCR4 | |
| SCHEMBL7093421 | 0.74 | ALDH1A1 (0.71) | MAPTMAPK1MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0580503-B1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |