Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TARS1 | P26639 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719362 | 0.81 | LMNA (0.50) | LMNASMN1; SMN2CA1CA2CA9 | |
| SCHEMBL13588869 | 0.81 | SOS1 (0.58) | SOS1LMNAHTTSMN1; SMN2FFAR1 | |
| Iodide SCHEMBL31414542 | 0.79 | LMNA (0.49) | LMNAHTTSMN1; SMN2CA1CA2 | |
| SCHEMBL11797040 | 0.78 | SOS1 (0.64) | SOS1LMNAHTTSMN1; SMN2FFAR1 | |
| SCHEMBL9249109 | 0.78 | SOS1 (0.64) | SOS1LMNAHTTSMN1; SMN2FFAR1 | |
| SCHEMBL8164394 | 0.78 | CA12 (0.54) | LMNACA1CA2CA9MMP1 | |
| SCHEMBL6123058 | 0.77 | HTT (0.81) | SOS1LMNAHTTSMN1; SMN2FFAR1 | |
| SCHEMBL17559302 | 0.77 | HTT (0.81) | SOS1LMNAHTTSMN1; SMN2FFAR1 | |
| SCHEMBL146566 | 0.77 | HTT (0.81) | SOS1LMNAHTTSMN1; SMN2FFAR1 | |
| SCHEMBL11415437 | 0.77 | HTT (0.81) | SOS1LMNAHTTSMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175302-A | Nucleophilic fluoroalkylation of aldehydes | ETHYL CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-4999429-A | Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives | ETHYL CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| US-4837327-A | Process for nucleophilic fluoroalkylation of aldehydes | ETHYL CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |