Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734093 | 1.00 | KMT2A (0.34) | KMT2AKDM4ELMNAMAPTNPSR1 | |
| SCHEMBL9533240 | 0.91 | AGTR1 (0.38) | KMT2AAGTR1AGTR2 | |
| SCHEMBL9533244 | 0.91 | AGTR1 (0.38) | KMT2AAGTR1AGTR2 | |
| SCHEMBL9705099 | 0.85 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9554407 | 0.83 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9554409 | 0.83 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9554283 | 0.79 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9554281 | 0.79 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9705225 | 0.79 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9553746 | 0.79 | AGTR1 (0.42) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087634-A | N-substituted imidazol-2-one compounds for treatment of circulatory disorders | G. D. SEARLE & CO. (US) | 1992-02-11 | — | — | US | disclosed |