SCHEMBL9734226

SCHEMBL9734226

O=[N+]([O-])c1cc([N+](=O)[O-])c2cc3ccccc3cc2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.74
TSHR P16473 1/20 0.74
MEN1 O00255 6/20 0.62
KMT2A Q03164 6/20 0.62
RAB9A P51151 4/20 0.62
HPRT1 P00492 1/20 0.49
ALDH1A1 P00352 6/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 4/20 0.47
MITF O75030 2/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
CASP6 P55212 1/20 0.45
NPC1 O15118 3/20 0.42
ATM Q13315 1/20 0.42
KDM4E B2RXH2 2/20 0.42
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57381 0.85 TDP1 (1.00) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL29475186 0.85 TDP1 (1.00) TDP1TSHRMEN1KMT2ARAB9A
Methane SCHEMBL28603558 0.84 TDP1 (0.96) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL29720550 0.79 TDP1 (0.70) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL30696914 0.79 ALDH1A1 (0.68) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL579426 0.79 ALDH1A1 (0.68) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL28257118 0.78 TDP1 (0.54) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL28197400 0.78 TDP1 (0.54) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL5167844 0.78 ALDH1A1 (0.66) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL31722809 0.78 TDP1 (0.68) TDP1TSHRMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086128-A HIGH MOLECULAR WEIGHT ARYLENE SULPHIDE POLYMER MELT MIXED WITH AROMATIC NITRO COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed