Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.55 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733570 | 0.82 | AGTR1 (0.49) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9210970 | 0.70 | AGTR1 (0.52) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL3906504 | 0.69 | BRS3 (0.70) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9037203 | 0.69 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9036174 | 0.69 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9036827 | 0.68 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9036573 | 0.67 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9036262 | 0.67 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9036866 | 0.67 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9037303 | 0.67 | AGTR1 (0.63) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087634-A | N-substituted imidazol-2-one compounds for treatment of circulatory disorders | G. D. SEARLE & CO. (US) | 1992-02-11 | — | — | US | claimed |