Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 8/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532908 | 0.72 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8885452 | 0.71 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL363 | 0.71 | AGTR1 (0.73) | AGTR1AGTR2 | |
| SCHEMBL9734324 | 0.70 | AGTR1 (0.55) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9879808 | 0.70 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL3906504 | 0.69 | BRS3 (0.70) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL7907661 | 0.69 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9126087 | 0.69 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL202160 | 0.69 | LTB4R2 (0.61) | AGTR1LTB4R2 | |
| SCHEMBL9036827 | 0.69 | AGTR1 (0.62) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427463-B1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORP (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5248689-A | Hypotensive agents, congestive heart failure, renal failure or glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0427463-A1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-15 | — | — | EP | disclosed |