Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 16/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709633 | 0.86 | TBXAS1 (0.50) | HRH1CYP2A6TBXAS1TBXA2RCYP3A4 | |
| SCHEMBL9732269 | 0.83 | TBXAS1 (0.60) | HRH1CYP2A6TBXAS1TBXA2R | |
| SCHEMBL9732792 | 0.80 | TBXAS1 (0.47) | TBXAS1CYP3A4 | |
| SCHEMBL9733052 | 0.80 | TBXAS1 (0.47) | TBXAS1CYP3A4 | |
| SCHEMBL9732760 | 0.79 | TBXAS1 (0.53) | HRH1CYP2A6TBXAS1CYP3A4 | |
| SCHEMBL29059890 | 0.79 | TBXAS1 (0.51) | TBXAS1CYP3A4 | |
| SCHEMBL9732879 | 0.78 | HRH1 (0.51) | HRH1CYP2A6TBXAS1CYP3A4 | |
| SCHEMBL9733069 | 0.78 | HRH1 (0.56) | HRH1CYP2A6TBXAS1CYP3A4 | |
| SCHEMBL9732387 | 0.76 | CYP2A6 (0.49) | HRH1CYP2A6TBXAS1CYP3A4 | |
| SCHEMBL9732023 | 0.75 | TBXAS1 (0.53) | HRH1CYP2A6TBXAS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-5025025-A | Cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |