Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | PPARA | Q07869 | 10/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734501 | 0.85 | KDM4E (0.50) | PPARGPPARAKLK5MEN1ALDH1A1 | |
| SCHEMBL14038361 | 0.82 | ESR2 (0.41) | PPARGPPARAKLK5MIFMEN1 | |
| SCHEMBL14013303 | 0.77 | PPARG (0.60) | PPARGPPARAKLK5ALDH1A1 | |
| SCHEMBL9938371 | 0.76 | GABRA1 (0.47) | MIFGABRA1GABRB2MEN1ALDH1A1 | |
| SCHEMBL23360606 | 0.75 | GABRA1 (0.46) | MIFGABRA1GABRB2ALDH1A1ESR1 | |
| SCHEMBL5117961 | 0.75 | PPARG (0.70) | PPARGPPARA | |
| SCHEMBL14007732 | 0.73 | ESR2 (0.43) | MIFMEN1ALDH1A1KMT2AESR1 | |
| SCHEMBL28999667 | 0.73 | PPARG (0.54) | PPARGPPARAMEN1ALDH1A1KMT2A | |
| SCHEMBL28999685 | 0.72 | PPARG (0.48) | PPARGPPARAMEN1ALDH1A1KMT2A | |
| SCHEMBL2069508 | 0.72 | ALDH1A1 (0.59) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456205-B2 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-25 | — | — | US | disclosed |
| US-7456205-B2 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-25 | — | — | US | disclosed |
| US-20060178405-A1 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2006-08-10 | — | — | US | disclosed |
| EP-1598345-A1 | BENZOPYRAN COMPOUNDS, PROCESS FOR PREPARING THE SAME AND THEIR USE | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2005-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178405-A1 | Benzopyran compounds, process for preparing the same and their use | SLC5A2, CYP2D6, IAPP | PPARG 670/4885PPARA 414/4885KLK5 2713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.