SCHEMBL9734602

SCHEMBL9734602

COC(=O)C(CCN1CCCCCC1)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 9/20 0.54
TACR2 P21452 5/20 0.53
SLC6A2 P23975 2/20 0.49
SLC6A4 P31645 2/20 0.49
TACR1 P25103 4/20 0.49
SIGMAR1 Q99720 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
TSHR P16473 1/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
MEN1 O00255 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MCHR1 Q99705 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8095001 0.88 SLC6A3 (0.55) SLC6A3TACR2SLC6A2SLC6A4TACR1
SCHEMBL3637256 0.85 SLC6A3 (0.45) SLC6A3TACR2SLC6A2SLC6A4TACR1
SCHEMBL8048710 0.82 SLC6A3 (0.50) SLC6A3TACR2SLC6A2SLC6A4TACR1
SCHEMBL295129 0.82 SLC6A3 (0.49) SLC6A3TACR2SLC6A2SLC6A4TACR1
SCHEMBL631558 0.78 SLC6A3 (0.50) SLC6A3SLC6A2SLC6A4TSHRHTT
SCHEMBL10651698 0.77 SLC6A3 (0.49) SLC6A3SLC6A2SLC6A4HTT
SCHEMBL10650297 0.77 SLC6A3 (0.49) SLC6A3SLC6A2SLC6A4HTT
SCHEMBL2646900 0.77 SLC6A3 (0.49) SLC6A3SLC6A2SLC6A4HTT
SCHEMBL632673 0.76 SLC6A3 (0.48) SLC6A3SLC6A2SLC6A4HTT
SCHEMBL10650293 0.76 SLC6A3 (0.48) SLC6A3SLC6A2SLC6A4TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089251-A AROMATIC DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS SANOFI (FR) 1992-02-18 US disclosed
US-4916156-A ANTISEPTIC OR PRESERVATIVES IN PHARMACY, COSMETOLOGY OR FOOD STUFF SANOFI (FR) 1990-04-10 US disclosed