Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31438434 | 0.79 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL962547 | 0.78 | TP53 (0.54) | CYP1A2CYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL21045059 | 0.77 | POLB (0.38) | CYP1A2CYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL17114041 | 0.76 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL17196907 | 0.76 | CYP1A2 (0.77) | CYP1A2CYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL3660587 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL28112902 | 0.74 | SLC6A2 (0.44) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2308910 | 0.74 | CYP1A2 (0.72) | CYP1A2CYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL2355777 | 0.74 | CYP1A2 (0.72) | CYP1A2CYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL27581441 | 0.74 | LMNA (0.56) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143953-A | N-alkyl maleimide thermal stabilizers for vinyl halide polymers | THE B. F. GOODRICH COMPANY (US) | 1992-09-01 | — | — | US | claimed |
| US-5143953-A | N-alkyl maleimide thermal stabilizers for vinyl halide polymers | THE B. F. GOODRICH COMPANY (US) | 1992-09-01 | — | — | US | disclosed |