Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734325 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP2D6CYP2C19LMNACYP1A2 | |
| SCHEMBL1703503 | 0.80 | ALDH1A1 (0.70) | ALDH1A1CYP2D6CYP2C19LMNACYP1A2 | |
| SCHEMBL4516377 | 0.78 | HIF1A (0.53) | ALDH1A1CYP2D6CYP2C19LMNACYP1A2 | |
| SCHEMBL9733681 | 0.76 | ALDH1A1 (0.45) | ALDH1A1CYP2D6CYP2C19LMNACYP1A2 | |
| SCHEMBL9733265 | 0.75 | ATM (0.48) | ALDH1A1CYP2D6CYP2C19LMNACYP1A2 | |
| SCHEMBL13180853 | 0.74 | LMNA (0.70) | ALDH1A1CYP2D6CYP2C19LMNACYP1A2 | |
| SCHEMBL9733390 | 0.74 | ALDH1A1 (0.43) | ALDH1A1CYP2D6CYP2C19LMNACYP1A2 | |
| SCHEMBL9733985 | 0.74 | ALDH1A1 (0.43) | ALDH1A1CYP2D6CYP2C19LMNACYP1A2 | |
| SCHEMBL3699711 | 0.73 | LMNA (1.00) | ALDH1A1CYP2D6CYP2C19LMNACYP1A2 | |
| SCHEMBL14627842 | 0.70 | LMNA (0.65) | ALDH1A1CYP2D6CYP2C19LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |