SCHEMBL9734869

SCHEMBL9734869

CCCCCS(=O)(=O)C(F)F

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.61
FAAH O00519 6/20 0.52
CES1 P23141 5/20 0.38
CES2 O00748 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7641252 0.98 CA2 (0.64) CA2FAAHCES1CES2
SCHEMBL496689 0.85 CA2 (0.73) CA2FAAHCES1CES2
SCHEMBL11897976 0.81
SCHEMBL8594180 0.79 CA2 (0.56) CA2FAAHCES1CES2
SCHEMBL13623537 0.77 CA2 (0.59) CA2FAAHCES1CES2
SCHEMBL10707328 0.77 CA2 (0.59) CA2FAAHCES1CES2
SCHEMBL5505478 0.77 CA2 (0.59) CA2FAAHCES1CES2
SCHEMBL1911477 0.75 CA2 (0.63) CA2FAAHCES1CES2
SCHEMBL14519882 0.75 CA2 (0.63) CA2FAAHCES1CES2
SCHEMBL20603733 0.75 CA2 (0.36) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4837327-A Process for nucleophilic fluoroalkylation of aldehydes ETHYL CORPORATION (US) 1989-06-06 US claimed
CN-108779067-A The preparation method of sulfoxide derivant 组合化学工业株式会社 2018-11-09 CN disclosed
US-5175302-A Nucleophilic fluoroalkylation of aldehydes ETHYL CORPORATION (US) 1992-12-29 US disclosed
US-5175302-A Nucleophilic fluoroalkylation of aldehydes ETHYL CORPORATION (US) 1992-12-29 US disclosed
US-4999429-A Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives ETHYL CORPORATION (US) 1991-03-12 US disclosed
US-4999429-A Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives ETHYL CORPORATION (US) 1991-03-12 US disclosed
US-4837327-A Process for nucleophilic fluoroalkylation of aldehydes ETHYL CORPORATION (US) 1989-06-06 US disclosed
US-4837327-A Process for nucleophilic fluoroalkylation of aldehydes ETHYL CORPORATION (US) 1989-06-06 US disclosed