Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380016 | 0.89 | KDM4E (0.59) | KDM4EALDH1A1GAATDP1LMNA | |
| SCHEMBL9734904 | 0.88 | MAPK1 (0.43) | KDM4EALDH1A1GAATDP1MPO | |
| SCHEMBL9733752 | 0.88 | ALDH1A1 (0.68) | KDM4EALDH1A1GAATDP1LMNA | |
| SCHEMBL7735651 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1GAATDP1MEN1 | |
| SCHEMBL9734301 | 0.86 | ALDH1A1 (0.66) | KDM4EALDH1A1GAATDP1LMNA | |
| SCHEMBL9734442 | 0.86 | MAPT (0.55) | KDM4EALDH1A1GAATDP1MPO | |
| SCHEMBL9734467 | 0.85 | ALDH1A1 (0.68) | KDM4EALDH1A1GAATDP1LMNA | |
| SCHEMBL9734058 | 0.83 | ALDH1A1 (0.56) | KDM4EALDH1A1GAATDP1MPO | |
| SCHEMBL9734580 | 0.82 | GAA (0.43) | KDM4EALDH1A1GAATDP1MPO | |
| SCHEMBL9734761 | 0.82 | CD274 (0.46) | KDM4EALDH1A1GAATDP1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0434185-A2 | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-26 | — | — | EP | disclosed |