Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734929 | 0.82 | KDM4E (0.51) | GAAKDM4EALDH1A1TDP1LMNA | |
| SCHEMBL10565334 | 0.81 | PDE5A (0.39) | GAAKDM4ETDP1LMNAMEN1 | |
| SCHEMBL10564840 | 0.80 | PDE5A (0.38) | GAAKDM4ETDP1LMNAMEN1 | |
| SCHEMBL10566223 | 0.80 | PDE5A (0.38) | GAAKDM4ETDP1LMNAMEN1 | |
| SCHEMBL8772352 | 0.79 | SHBG (0.44) | KDM4EMEN1KMT2ANUDT1BACE1 | |
| SCHEMBL9182898 | 0.77 | NUDT1 (0.44) | KDM4EMEN1KMT2ANUDT1BACE1 | |
| SCHEMBL27861753 | 0.77 | NUDT1 (0.48) | KDM4ETDP1LMNAMEN1KMT2A | |
| SCHEMBL10563172 | 0.77 | PDE5A (0.38) | GAAKDM4ETDP1LMNAMEN1 | |
| SCHEMBL10566115 | 0.77 | PDE5A (0.38) | GAAKDM4ETDP1LMNAMEN1 | |
| SCHEMBL9186132 | 0.76 | NUDT1 (0.43) | KDM4EMEN1KMT2ANUDT1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0434185-A2 | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-26 | — | — | EP | disclosed |