Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | ACR | P10323 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014968 | 0.95 | THRA (0.60) | THRATHRBPRSS1ACRSMN1; SMN2 | |
| SCHEMBL7953848 | 0.90 | THRB (0.54) | THRATHRBPRSS1ACRSMN1; SMN2 | |
| SCHEMBL9513365 | 0.88 | THRA (0.57) | THRATHRBPRSS1ACRSMN1; SMN2 | |
| SCHEMBL9506640 | 0.86 | NPC1 (0.56) | THRATHRBSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL9507747 | 0.86 | NPC1 (0.56) | THRATHRBSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL9508417 | 0.86 | NPC1 (0.56) | THRATHRBSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL9504565 | 0.86 | NPC1 (0.56) | THRATHRBSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL11664466 | 0.86 | NPC1 (0.56) | THRATHRBSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL11405601 | 0.86 | THRA (0.55) | THRATHRBPRSS1ACRSMN1; SMN2 | |
| SCHEMBL11513305 | 0.86 | THRB (0.49) | THRATHRBPRSS1ACRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098599-A | Aromatic esters with sulfide groups as liquid crystals | MITSUBISHI RAYON COMPANY LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0354355-A1 | Optically active compound and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |