SCHEMBL9735377

SCHEMBL9735377

CC(=O)Oc1ccc(C(=O)Oc2ccc(O)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.56
HSD17B10 Q99714 2/20 0.55
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
LMNA P02545 3/20 0.53
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ESR1 P03372 3/20 0.49
PGR P06401 1/20 0.49
CHRM2 P08172 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
AR P10275 1/20 0.49
CHRM1 P11229 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9760675 0.92 ELANE (0.64) ELANEHSD17B10LMNAMAPTTDP1
SCHEMBL8850878 0.92 ELANE (0.64) ELANEHSD17B10LMNAMAPTTDP1
SCHEMBL16429668 0.90 APP (0.50) ELANEHSD17B10CA12CA1CA2
SCHEMBL16493489 0.90 HSD17B10 (0.59) ELANEHSD17B10CA12CA1CA2
SCHEMBL740606 0.90 HSD17B10 (0.59) ELANEHSD17B10CA12CA1CA2
SCHEMBL777813 0.90 HSD17B10 (0.59) ELANEHSD17B10CA12CA1CA2
SCHEMBL9696072 0.90 HSD17B10 (0.59) ELANEHSD17B10CA12CA1CA2
SCHEMBL688276 0.90 HSD17B10 (0.59) ELANEHSD17B10CA12CA1CA2
SCHEMBL9786890 0.89 HSD17B1 (0.59) ELANEHSD17B10CA12CA1CA2
SCHEMBL17722444 0.88 ELANE (0.65) ELANEHSD17B10CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098599-A Aromatic esters with sulfide groups as liquid crystals MITSUBISHI RAYON COMPANY LTD. (JP) 1992-03-24 US disclosed
EP-0354355-A1 Optically active compound and liquid crystal composition MITSUBISHI RAYON CO., LTD. (JP) 1990-02-14 EP disclosed