Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 5/20 | 0.40 |
| ▸ | PRKCA | P17252 | 4/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.39 |
| ▸ | PRKCG | P05129 | 3/20 | 0.39 |
| ▸ | PRKCB | P05771 | 3/20 | 0.39 |
| ▸ | PRKCH | P24723 | 3/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.39 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670112 | 0.86 | PDCD4 (0.41) | PDCD4PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL9735225 | 0.85 | TOP1 (0.40) | PDCD4GLS2DAGLATOP1 | |
| SCHEMBL7296014 | 0.77 | PDCD4 (0.47) | PDCD4DAGLATOP1 | |
| SCHEMBL9671687 | 0.77 | PRKCA (0.40) | PDCD4PRKCA | |
| SCHEMBL8985076 | 0.73 | PDCD4 (0.47) | PDCD4GLS2 | |
| SCHEMBL9148184 | 0.73 | PDCD4 (0.42) | PDCD4GLS2DAGLA | |
| SCHEMBL7294590 | 0.73 | PDCD4 (0.47) | PDCD4GLS2 | |
| SCHEMBL9671381 | 0.73 | PDCD4 (0.47) | PDCD4GLS2 | |
| SCHEMBL14339054 | 0.73 | PDCD4 (0.47) | PDCD4GLS2 | |
| SCHEMBL9672604 | 0.73 | PDCD4 (0.47) | PDCD4GLS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |