Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888745 | 0.81 | MEN1 (0.50) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL1323885 | 0.81 | MEN1 (0.50) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL11365688 | 0.79 | SHBG (0.50) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL8960077 | 0.75 | — | — | |
| SCHEMBL57369 | 0.75 | MEN1 (0.57) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL11376493 | 0.75 | MEN1 (0.57) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL9142521 | 0.75 | GABRP (0.36) | — | |
| Ammonia Solution, Strong SCHEMBL11251682 | 0.73 | MEN1 (0.43) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL9392305 | 0.73 | SLC6A2 (0.52) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL26910 | 0.73 | MEN1 (0.55) | MEN1KMT2AKDM4EESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175185-A | Antiacne agents | ALLERGAN, INC. (US) | 1992-12-29 | — | — | US | disclosed |