Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867034 | 0.91 | SMN1; SMN2 (0.67) | KDM4ESMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9591445 | 0.90 | KDM4E (0.58) | KDM4ESMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10865751 | 0.88 | KDM4E (0.39) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL10867587 | 0.85 | SMN1; SMN2 (0.56) | KDM4ESMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10568364 | 0.83 | MEN1 (0.51) | KDM4ESMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9478178 | 0.82 | KDM4E (0.50) | KDM4ESMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10502876 | 0.81 | CA1 (0.44) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9735397 | 0.81 | SMN1; SMN2 (0.69) | KDM4ESMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10688914 | 0.81 | HCRTR1 (0.43) | KDM4ESMN1; SMN2HCRTR2 | |
| SCHEMBL10865204 | 0.78 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2CYP3A4LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880932-A | PLANT GROWTH REGULATORS, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-11-14 | — | — | US | disclosed |
| EP-0121082-B1 | GUANIDIN DERIVATIVES | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |
| US-4844730-A | PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| US-4797484-A | REACTING GUANIDINE DERIVATIVE WITH SULPHONYL HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| US-4743294-A | N'-(substituted-1,3,5-triazin-2-yl)-N\"-amino-N\"'-(substituted-benzenesulphonyl)-guanidines as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-10 | — | — | US | disclosed |
| US-4725305-A | PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-02-16 | — | — | US | disclosed |
| US-4725303-A | N'-(substituted-pyrimidin-2-yl)-N\"-amino-N\"'-(substituted-benzenesulphonyl)-guanidines as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1988-02-16 | — | — | US | disclosed |
| US-4721785-A | FOR THE 2-GUANIDINE DERIVATIVE HERBICIDE PRODUCTS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-01-26 | — | — | US | disclosed |
| US-4602938-A | N'-(substituted-pyrimidin-2-yl)-N\"-substituted-N\",N\"'-bis-(substituted-benzenesulphonyl)-guanidines as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-29 | — | — | US | disclosed |
| EP-0121082-A1 | Guanidin derivatives | BAYER AG (DE) | 1984-10-10 | — | — | EP | disclosed |