Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502876 | 0.91 | CA1 (0.44) | CA1CA2CA5ACA9KDM4E | |
| SCHEMBL6054812 | 0.91 | CA1 (0.50) | CA1CA2CA5ACA9KDM4E | |
| SCHEMBL9587146 | 0.88 | CA1 (0.41) | CA1CA2CA5ACA9KDM4E | |
| SCHEMBL9743094 | 0.88 | CA1 (0.47) | CA1CA2CA5ACA9MAPT | |
| SCHEMBL9587373 | 0.86 | CA1 (0.48) | CA1CA2CA5ACA9MAPT | |
| SCHEMBL9588694 | 0.82 | EDNRA (0.43) | MAPTKMT2AMEN1 | |
| SCHEMBL9586448 | 0.81 | CA1 (0.40) | CA1CA2CA5ACA9KDM4E | |
| SCHEMBL9591445 | 0.80 | KDM4E (0.58) | CA1CA2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10865204 | 0.79 | ALDH1A1 (0.41) | KDM4EHSD17B10SMN1; SMN2KMT2ATDP1 | |
| SCHEMBL9474698 | 0.78 | KDM4E (0.39) | KDM4EHSD17B10SMN1; SMN2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5092917-A | HERBICIDAL AMINOGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | claimed |
| US-5211740-A | Applying triazinyl sulfonylguanidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-18 | — | — | US | disclosed |
| US-5211740-A | Applying triazinyl sulfonylguanidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-18 | — | — | US | disclosed |
| US-5092917-A | HERBICIDAL AMINOGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5092917-A | HERBICIDAL AMINOGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| EP-0343462-A1 | Aminoguanidino azines | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |