SCHEMBL9735647

SCHEMBL9735647

CNC(=O)COC(C)C(C)OCC(=O)NC

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
LMNA P02545 3/20 0.36
MCL1 Q07820 1/20 0.36
KDM4E B2RXH2 2/20 0.35
POLB P06746 2/20 0.34
CYP2D6 P10635 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KCNH2 Q12809 1/20 0.34
ALDH1A1 P00352 4/20 0.32
MAPT P10636 2/20 0.32
APLNR P35414 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9911442 0.85
SCHEMBL19821852 0.79 BCHE (0.39) BCHEACHELMNAMCL1KDM4E
SCHEMBL24906960 0.79 BCHE (0.39) BCHEACHELMNAMCL1KDM4E
SCHEMBL24906741 0.78 BCHE (0.35) BCHEACHELMNAMCL1POLB
SCHEMBL21306881 0.78 BCHE (0.35) BCHEACHELMNAMCL1POLB
SCHEMBL10263889 0.76 BCHE (0.37) BCHEACHELMNAMCL1KDM4E
SCHEMBL18598077 0.76 BCHE (0.34) BCHEACHELMNAMCL1KDM4E
SCHEMBL13793691 0.73 NPC1 (0.45) BCHEACHELMNAMCL1KDM4E
SCHEMBL15836123 0.73 BCHE (0.33) BCHEACHEALDH1A1MAPTCHRNB2
SCHEMBL13411713 0.73 LMNA (0.42) BCHEACHELMNAMCL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0235470-B1 ION-SENSITIVE FET SENSOR TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1992-11-11 EP claimed
US-20240366627-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2024-11-07 US disclosed
US-11963964-B2 Small molecules for mouse satellite cell proliferation PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366627-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 BCHE 2345/4885ACHE 745/4885LMNA 1250/4885
US-11963964-B2 Small molecules for mouse satellite cell proliferation MKI67, MYLK2, MYH2 BCHE 2345/4885ACHE 745/4885LMNA 1250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.