Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 15/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347927 | 0.75 | HRH4 (0.35) | HRH4KMT2AHTR3AHTR6 | |
| SCHEMBL9255695 | 0.73 | ALDH1A1 (0.36) | KMT2A | |
| SCHEMBL9843398 | 0.60 | HRH4 (0.38) | HRH4KMT2AHTR3AHTR6 | |
| SCHEMBL9250851 | 0.60 | POLB (0.34) | KMT2A | |
| SCHEMBL10322861 | 0.58 | KCNK2 (0.49) | HRH4KMT2AHTR3AHTR6 | |
| SCHEMBL27082996 | 0.58 | HRH4 (0.59) | HRH4KMT2AHTR3AHTR6 | |
| SCHEMBL5032275 | 0.58 | HRH4 (0.78) | HRH4HTR6 | |
| SCHEMBL26037956 | 0.56 | HRH4 (0.61) | HRH4KMT2AHTR3A | |
| SCHEMBL3566311 | 0.56 | HRH4 (0.50) | HRH4KMT2AHTR3A | |
| SCHEMBL13787121 | 0.56 | HRH4 (0.51) | HRH4KMT2AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175163-A | Tranquilizer, antidepresant, antispasmodic, analgesic and antiinflammatory agent | EGIS GYOGYSZERGYAR (HU) | 1992-12-29 | — | — | US | disclosed |