Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 15/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26580968 | 0.83 | HRH4 (0.55) | HRH4KMT2AHTR3A | |
| SCHEMBL27082996 | 0.79 | HRH4 (0.59) | HRH4KMT2AHTR3A | |
| SCHEMBL20604725 | 0.79 | KMT2A (0.56) | HRH4KMT2A | |
| SCHEMBL5032275 | 0.78 | HRH4 (0.78) | HRH4 | |
| SCHEMBL3094653 | 0.78 | ALDH1A1 (0.56) | HRH4KMT2A | |
| SCHEMBL23809147 | 0.76 | HRH4 (0.53) | HRH4KMT2A | |
| SCHEMBL4369596 | 0.76 | HRH4 (1.00) | HRH4 | |
| SCHEMBL22924654 | 0.76 | HRH4 (0.74) | HRH4KMT2AHTR3A | |
| SCHEMBL12257800 | 0.76 | HRH4 (0.74) | HRH4KMT2AHTR3A | |
| SCHEMBL20604872 | 0.75 | HRH4 (0.47) | HRH4KMT2AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423435-B1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | UNIV VANDERBILT (US) | 2023-08-23 | — | — | EP | disclosed |