Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131369 | 0.82 | CYP1A2 (0.39) | CYP1A2CASP1CASP3CASP7CASP6 | |
| SCHEMBL9734858 | 0.81 | CYP1A2 (0.38) | CYP1A2CASP1CASP3CASP7CASP6 | |
| SCHEMBL9734854 | 0.79 | CYP1A2 (0.37) | CYP1A2CASP1CASP3CASP7CASP6 | |
| SCHEMBL8985074 | 0.79 | CYP1A2 (0.37) | CYP1A2CASP1CASP3CASP7CASP6 | |
| SCHEMBL9735251 | 0.77 | CYP1A2 (0.35) | CYP1A2CASP1CASP3CASP7CASP6 | |
| SCHEMBL9743200 | 0.76 | CYP1A2 (0.35) | CYP1A2CASP1CASP3CASP7CASP6 | |
| SCHEMBL9734235 | 0.75 | CYP1A2 (0.38) | CYP1A2HCAR2HDAC1HDAC8NPC1 | |
| SCHEMBL8985071 | 0.69 | HDAC1 (0.40) | CYP1A2CASP1CASP3CASP7CASP6 | |
| SCHEMBL9671162 | 0.64 | CYP1A2 (0.33) | CYP1A2CASP1CASP3CASP7CASP6 | |
| SCHEMBL4625658 | 0.64 | SIGMAR1 (0.58) | CYP1A2HDAC1HDAC8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0372941-A2 | Anti-inflammatory 5-hydroxy-2-furanones | ALLERGAN, INC (US) | 1990-06-13 | — | — | EP | disclosed |