Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735736 | 1.00 | MAPT (0.51) | MAPTNPC1ALDH1A1RAB9AALOX12 | |
| SCHEMBL9734847 | 0.82 | SMN1; SMN2 (0.49) | MAPTNPC1ALDH1A1RAB9ACA1 | |
| SCHEMBL9734844 | 0.82 | SMN1; SMN2 (0.49) | MAPTNPC1ALDH1A1RAB9ACA1 | |
| Hydrochloric Acid SCHEMBL9736367 | 0.81 | SMN1; SMN2 (0.48) | MAPTNPC1ALDH1A1RAB9ACA1 | |
| Hydrochloric Acid SCHEMBL9736370 | 0.81 | SMN1; SMN2 (0.48) | MAPTNPC1ALDH1A1RAB9ACA1 | |
| SCHEMBL9735087 | 0.81 | CA1 (0.48) | MAPTNPC1ALDH1A1RAB9ACA1 | |
| SCHEMBL9735084 | 0.81 | CA1 (0.48) | MAPTNPC1ALDH1A1RAB9ACA1 | |
| SCHEMBL9735705 | 0.81 | RAB9A (0.49) | MAPTNPC1ALDH1A1RAB9ACA1 | |
| SCHEMBL9735698 | 0.81 | RAB9A (0.49) | MAPTNPC1ALDH1A1RAB9ACA1 | |
| SCHEMBL9736491 | 0.80 | NPC1 (0.48) | MAPTNPC1ALDH1A1RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112866-A | Sulfonylfluorides as intermediates, also useful in treatment of bone disorders, antisecretory, antiulcer | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |