Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 6/20 | 0.54 |
| ▸ | ACHE | P22303 | 6/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.54 |
| ▸ | GABRD | O14764 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | GABRE | P78334 | 1/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165786 | 0.74 | KMT2A (0.64) | HRH3ACHE | |
| SCHEMBL9874141 | 0.73 | BCHE (0.54) | BCHEACHEGABRPGABRDAPP | |
| SCHEMBL9875958 | 0.72 | — | — | |
| SCHEMBL24000133 | 0.72 | BCHE (0.97) | BCHEACHEGABRPGABRDAPP | |
| SCHEMBL13480729 | 0.72 | BCHE (0.92) | BCHEACHEGABRPGABRDAPP | |
| SCHEMBL15168191 | 0.71 | ACHE (1.00) | BCHEACHEGABRPGABRDAPP | |
| SCHEMBL12059555 | 0.71 | ACHE (1.00) | BCHEACHEGABRPGABRDAPP | |
| SCHEMBL24164216 | 0.71 | ACHE (1.00) | BCHEACHEGABRPGABRDAPP | |
| SCHEMBL29486236 | 0.71 | ACHE (1.00) | BCHEACHEGABRPGABRDAPP | |
| Hydrochloric Acid SCHEMBL29711388 | 0.70 | BCHE (1.00) | BCHEACHEGABRPGABRDAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112830-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | claimed |