Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.62 |
| ▸ | BCHE | P06276 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.62 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.62 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735659 | 0.91 | ACHE (0.68) | ACHEBCHEHSD17B10ALDH1A1TSHR | |
| SCHEMBL9734944 | 0.89 | ACHE (0.69) | ACHEBCHEHSD17B10ALDH1A1TSHR | |
| SCHEMBL9167709 | 0.88 | ACHE (0.62) | ACHEBCHEHSD17B10ALDH1A1TSHR | |
| SCHEMBL9737220 | 0.82 | ACHE (0.68) | ACHEBCHEHSD17B10ALDH1A1TSHR | |
| SCHEMBL9168351 | 0.81 | ACHE (0.65) | ACHEBCHECHRM1GRIN1GRIN2A | |
| Fumaric Acid SCHEMBL9170862 | 0.78 | TSHR (0.69) | ACHEBCHEHSD17B10ALDH1A1TSHR | |
| Fumaric Acid SCHEMBL9170857 | 0.78 | TSHR (0.69) | ACHEBCHEHSD17B10ALDH1A1TSHR | |
| SCHEMBL9735562 | 0.78 | FABP6 (0.43) | ACHEBCHEHSD17B10ALDH1A1TSHR | |
| SCHEMBL5047992 | 0.77 | ACHE (1.00) | ACHEBCHEHSD17B10ALDH1A1TSHR | |
| Tacrine SCHEMBL2828 | 0.77 | ACHE (1.00) | ACHEBCHEHSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112830-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | claimed |