Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736524 | 0.78 | PTGS1 (0.46) | PTGS1PTGS2XDHABCB1CA12 | |
| SCHEMBL9736544 | 0.74 | ABCB1 (0.41) | ABCB1 | |
| SCHEMBL9274003 | 0.74 | MAOB (0.37) | CHEK1ABCB1MEN1KMT2A | |
| SCHEMBL22939295 | 0.69 | BACE1 (0.32) | ABCB1MEN1KMT2A | |
| SCHEMBL506743 | 0.68 | CA12 (0.46) | PTGS1PTGS2XDHABCB1HIF1A | |
| SCHEMBL30523681 | 0.68 | CA12 (0.46) | PTGS1PTGS2XDHABCB1HIF1A | |
| SCHEMBL9736953 | 0.67 | ABCB1 (0.38) | ABCB1 | |
| SCHEMBL15633452 | 0.67 | KDM4C (0.39) | CHEK1KDM4CNPC1RAB9AMEN1 | |
| SCHEMBL8534981 | 0.67 | CA12 (0.40) | PTGS1PTGS2XDHABCB1HIF1A | |
| SCHEMBL5857069 | 0.66 | TACR1 (0.45) | KDM4CNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |