Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 6/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195542 | 0.84 | ABCC9 (0.41) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9736544 | 0.80 | ABCB1 (0.41) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7276260 | 0.78 | ABCC9 (0.45) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9274003 | 0.75 | MAOB (0.37) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8536595 | 0.69 | ABCC9 (0.49) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9372246 | 0.68 | ABCB1 (0.43) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9195508 | 0.68 | F10 (0.34) | — | |
| SCHEMBL9735945 | 0.67 | PTGS1 (0.36) | ABCB1 | |
| SCHEMBL7267396 | 0.67 | ABCC9 (0.46) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7267817 | 0.67 | ABCC9 (0.52) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |