Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523681 | 1.00 | CA12 (0.46) | CA12CA9ALDH1A1HPGDKDM4E | |
| SCHEMBL30065854 | 0.87 | ODC1 (0.44) | CA12CA9ALDH1A1HPGDKDM4E | |
| SCHEMBL20766474 | 0.87 | ODC1 (0.44) | CA12CA9ALDH1A1HPGDKDM4E | |
| SCHEMBL8129452 | 0.85 | HIF1A (0.38) | CA12CA9ALDH1A1HPGDKDM4E | |
| SCHEMBL9293857 | 0.82 | HIF1A (0.43) | HIF1AEPAS1 | |
| SCHEMBL9765461 | 0.80 | CA12 (0.43) | CA12CA9CYP3A4ABCB1PTGS1 | |
| SCHEMBL9042019 | 0.80 | HIF1A (0.44) | CA12CA9ALDH1A1HPGDKDM4E | |
| SCHEMBL9206139 | 0.78 | CA12 (0.40) | CA12CA9KDM4EABCB1PTGS1 | |
| SCHEMBL6980284 | 0.78 | CA12 (0.40) | CA12CA9KDM4EABCB1PTGS1 | |
| SCHEMBL9736524 | 0.78 | PTGS1 (0.46) | CA12CA9KDM4ECYP3A4ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643626-B1 | METHOD OF PRODUCING EPOXYCHROMANS WITH A CHIRAL CATALYST | RES CORP TECHNOLOGIES INC (US) | 2002-02-27 | — | — | EP | claimed |
| US-5663393-A | CYCLIZATION; DECYCLIZATION; HYDROLYSIS; HYDROGENATION | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-09-02 | — | — | US | claimed |
| US-5637739-A | ORGANOMETALLIC CATALYSTS FOR ENANTIOSELECTIVELY EPOXIDIZING PROCHIRAL OLEFINS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-06-10 | — | — | US | claimed |
| EP-0643626-A4 | CHIRAL CATALYSTS, CATALYTIC OXIDATION AND DISPROPORTIONATION REACTIONS, AND METHODS OF PRODUCING EPOXYCHROMANS AND TAXOL. | RES CORP TECHNOLOGIES INC (US) | 1995-12-06 | — | — | EP | claimed |
| EP-0409651-B1 | New Process for the preparation of anti-hypertensive benzopyran derivative | ALKALOIDA VEGYESZETI GYAR (HU) | 1995-05-03 | — | — | EP | claimed |
| EP-0643626-A1 | CHIRAL CATALYSTS, CATALYTIC OXIDATION AND DISPROPORTIONATION REACTIONS, AND METHODS OF PRODUCING EPOXYCHROMANS AND TAXOL | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-22 | — | — | EP | claimed |
| WO-1993003838-A1 | CHIRAL CATALYSTS, CATALYTIC OXIDATION AND DISPROPORTIONATION REACTIONS, AND METHODS OF PRODUCING EPOXYCHROMANS AND TAXOL | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-03-04 | — | — | WO | claimed |
| US-12454539-B2 | Controlled-delivery cromakalim prodrugs | QLARIS BIO, INC. (US) | 2025-10-28 | — | — | US | disclosed |
| EP-4635568-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA Pharmaceuticals Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-3672954-B1 | COMPOUNDS, SALTS THEREOF AND THEIR USE FOR THE TREATMENT OF DISEASES | ACADIA PHARM INC (US) | 2025-08-13 | — | — | EP | disclosed |
| US-20250197385-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARM INC (US) | 2025-06-19 | — | — | US | disclosed |
| US-12139477-B2 | Compounds, salts thereof and methods for treatment of diseases | ACADIA PHARMACEUTICALS INC. (US) | 2024-11-12 | — | — | US | disclosed |
| CN-117466803-A | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2024-01-30 | — | — | CN | disclosed |
| EP-0409651-A1 | New Process for the preparation of anti-hypertensive benzopyran derivative | ALKALOIDA VEGYESZETI GYAR (HU) | 1991-01-23 | — | — | EP | disclosed |
| EP-0389861-A1 | Benzopyran derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-03 | — | — | EP | disclosed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |
| EP-0344747-A1 | Benzopyran derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-06 | — | — | EP | disclosed |
| US-4758677-A | Cyanobenzano [b] pyrans | BEECHAM GROUP P.L.C (GB) | 1988-07-19 | — | — | US | disclosed |
| US-4391815-A | VASODILATION, HYPOTENSIVE | BEECHAM GROUP LIMITED (GB) | 1983-07-05 | — | — | US | disclosed |
| US-4251537-A | Hypotensive 3,4-dihydro-2,2-dimethyl-4-amino-2H-benzo[b]pyran-3-ols | BEECHAM GROUP LIMITED (GB) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12139477-B2 | Compounds, salts thereof and methods for treatment of diseases | SLC10A1, CYP27A1, CYP11B2 | CA12 604/4885CA9 512/4885ALDH1A1 240/4885 |
| US-12454539-B2 | Controlled-delivery cromakalim prodrugs | KCNJ1, KCNJ8, KCNJ11 | CA12 1104/4885CA9 654/4885ALDH1A1 2491/4885 |
| US-20250197385-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | SLC10A1, CYP27A1, CYP11B2 | CA12 604/4885CA9 512/4885ALDH1A1 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.