Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737528 | 0.76 | GALR3 (0.42) | — | |
| SCHEMBL9735954 | 0.75 | S1PR1 (0.35) | S1PR1S1PR5 | |
| SCHEMBL9613272 | 0.62 | TP53 (0.47) | AKR1C3AKR1C2 | |
| SCHEMBL9736283 | 0.61 | SRD5A1 (0.40) | AKR1C3AKR1C2 | |
| SCHEMBL9613258 | 0.57 | HSD17B10 (0.62) | AKR1C3AKR1C2 | |
| SCHEMBL12125696 | 0.56 | LCK (0.56) | AKR1C3AKR1C2 | |
| SCHEMBL806188 | 0.56 | NOTUM (0.54) | S1PR1AKR1C3AKR1C2 | |
| SCHEMBL30703015 | 0.55 | HTR2A (0.43) | S1PR1 | |
| SCHEMBL20921201 | 0.55 | MEN1 (0.46) | AKR1C3AKR1C2 | |
| Acetamide SCHEMBL27414047 | 0.54 | ALDH1A1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021678-A1 | LIPOXYGENASE INHIBITING PYRROLO [1,2a]INDOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-12-10 | — | — | WO | disclosed |