Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103472 | 0.81 | KMT2A (0.60) | KMT2APOLBRAD52KDM4EMEN1 | |
| SCHEMBL9108166 | 0.79 | KMT2A (0.57) | KMT2APOLBRAD52KDM4EMEN1 | |
| SCHEMBL9108274 | 0.79 | KMT2A (0.57) | KMT2APOLBRAD52KDM4EMEN1 | |
| SCHEMBL1868598 | 0.75 | RAD52 (1.00) | KMT2APOLBRAD52KDM4EMEN1 | |
| SCHEMBL10286345 | 0.73 | KMT2A (0.60) | KMT2APOLBRAD52KDM4EMEN1 | |
| Suronacrine SCHEMBL975421 | 0.73 | — | — | |
| SCHEMBL9171253 | 0.72 | KMT2A (0.59) | KMT2APOLBRAD52KDM4EMEN1 | |
| SCHEMBL10870031 | 0.70 | KDM4E (0.53) | KMT2AKDM4EMEN1HTT | |
| SCHEMBL10870026 | 0.69 | KDM4E (0.54) | KMT2AKDM4EMEN1HTT | |
| SCHEMBL8022948 | 0.69 | MEN1 (0.97) | KMT2AKDM4EMEN1HTTBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112830-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | claimed |