Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674128 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A3MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9123748 | 0.99 | MEN1 (0.50) | SLC6A2SLC6A3MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9123750 | 0.99 | MEN1 (0.50) | SLC6A2SLC6A3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9125192 | 0.84 | RAB9A (0.54) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9125199 | 0.84 | RAB9A (0.54) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9673808 | 0.77 | NPC1 (0.51) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9125443 | 0.76 | MAPT (0.41) | MAPT | |
| SCHEMBL9125451 | 0.76 | MAPT (0.41) | MAPT | |
| SCHEMBL11387099 | 0.74 | TDP1 (0.61) | SLC6A2SLC6A3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11387103 | 0.74 | TDP1 (0.61) | SLC6A2SLC6A3MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012137-A1 | NOVEL 3(2H)-PYRIDAZINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1992-07-23 | — | — | WO | disclosed |