SCHEMBL9125451

SCHEMBL9125451

CCN(CC)CCn1ncc(N2CCN(CC=Cc3ccccc3)CC2)c(Cl)c1=O

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9125443 1.00 MAPT (0.41) MAPT
SCHEMBL9125507 0.83 ALDH1A1 (0.47) MAPT
SCHEMBL9125502 0.83 ALDH1A1 (0.47) MAPT
SCHEMBL9736113 0.76 SLC6A2 (0.49) MAPT
SCHEMBL9674128 0.76 SLC6A2 (0.49) MAPT
Hydrochloric Acid SCHEMBL9123748 0.75 MEN1 (0.50) MAPT
Hydrochloric Acid SCHEMBL9123750 0.75 MEN1 (0.50) MAPT
SCHEMBL9763254 0.67 HTT (0.50) MAPT
SCHEMBL9125199 0.67 RAB9A (0.54) MAPT
SCHEMBL9125192 0.67 RAB9A (0.54) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5395934-A Antiarrhythmia agents and cardiovascular disorders EGIS GYOGYSZERGYAR (HU) 1995-03-07 US disclosed