Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736572 | 1.00 | F11 (0.37) | F11KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL4069849 | 0.89 | F11 (0.39) | F11KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL9737058 | 0.84 | F11 (0.37) | F11KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL9737053 | 0.84 | F11 (0.37) | F11KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL9735838 | 0.81 | MEN1 (0.42) | F11FAAHNPC1NPSR1MEN1 | |
| SCHEMBL9735831 | 0.81 | MEN1 (0.42) | F11FAAHNPC1NPSR1MEN1 | |
| SCHEMBL4064372 | 0.79 | NPC1 (0.36) | F11KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9736666 | 0.76 | CFTR (0.46) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL4837991 | 0.76 | F11 (0.38) | F11KDM4EALDH1A1NPC1MAPT | |
| SCHEMBL6211362 | 0.76 | NPC1 (0.35) | F11KDM4EHSD17B10NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005148-A1 | IMIDAZOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS | RHONE-POULENC RORER LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |