Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735831 | 1.00 | MEN1 (0.42) | MEN1KMT2AFAAHNPC1RAB9A | |
| SCHEMBL9736574 | 0.81 | F11 (0.37) | MEN1KMT2AFAAHNPC1NPSR1 | |
| SCHEMBL9736572 | 0.81 | F11 (0.37) | MEN1KMT2AFAAHNPC1NPSR1 | |
| SCHEMBL9737053 | 0.81 | F11 (0.37) | MEN1KMT2AFAAHNPC1FABP4 | |
| SCHEMBL9737058 | 0.81 | F11 (0.37) | MEN1KMT2AFAAHNPC1FABP4 | |
| SCHEMBL4069849 | 0.81 | F11 (0.39) | MEN1KMT2AFAAHNPC1NPSR1 | |
| SCHEMBL2846531 | 0.73 | FAAH (0.43) | MEN1KMT2AFAAHNPC1F11 | |
| SCHEMBL4064372 | 0.72 | NPC1 (0.36) | NPC1NPSR1F11 | |
| SCHEMBL16497631 | 0.71 | MEN1 (0.45) | MEN1KMT2ANPC1F11 | |
| SCHEMBL9525207 | 0.71 | MAPK14 (0.43) | NPC1F11LMNAL3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005148-A1 | IMIDAZOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS | RHONE-POULENC RORER LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |